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BACE1 Dependent Neuregulin Processing: Review

1 Feb 2012

Abstract excerpt

Neuregulin-1 (NRG1), known also as heregulin, acetylcholine receptor inducing activity (ARIA), glial growth factor (GGF), or sensory and motor neuron derived factor (SMDF), plays essential roles in several developmental processes, and is required also later in life. Many variants of NRG1 are produced via alternative splicing and usage of distinct promoters. All contain an epidermal growth factor (EGF)-like...

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PMID: 22455478
DOI: 10.2174/156720512799361637

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