Article
A decrease of reelin expression as a putative vulnerability factor in schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America - 22 Dec 1998
Impagnatiello F, Guidotti A R, Pesold C, Dwivedi Y, Caruncho H, Pisu M G, Uzunov D P, Smalheiser N R, Davis J M, Pandey G N, Pappas G D, Tueting P, Sharma R P, Costa E
Abstract excerpt
Postmortem prefrontal cortices (PFC) (Brodmann's areas 10 and 46), temporal cortices (Brodmann's area 22), hippocampi, caudate nuclei, and cerebella of schizophrenia patients and their matched nonpsychiatric subjects were compared for reelin (RELN) mRNA and reelin (RELN) protein content. In all o...
Topics
- Age of Onset
- Aged
- Alternative Splicing
- Animals
- Brain
- Cell Adhesion Molecules, Neuronal
- Extracellular Matrix Proteins
- Gene Expression Regulation
- Genetic Variation
- Humans
- Mice
- Mice, Neurologic Mutants
- Middle Aged
- Nerve Tissue Proteins