Article
Elevated neuregulin-1 and ErbB4 protein in the prefrontal cortex of schizophrenic patients.
Schizophrenia research - 1 Mar 2008
Chong Victor Z, Thompson Mia, Beltaifa Senda, Webster Maree J, Law Amanda J, Weickert Cynthia Shannon
Abstract excerpt
Neuregulin-1 (NRG1) and its receptor, ErbB4, have been implicated in schizophrenia at both gene and transcript levels. The present investigation compared NRG1 and ErbB4 protein levels in prefrontal cortical (PFC) cytoplasmic and nuclear fractions among normal, schizophrenic, bipolar and major depressed subjects from the Stanley Consortium. We used immunoblotting procedures to examine potential NRG1 and ErbB4...
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