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Article

Neuregulin 1 and schizophrenia.

Annals of medicine - 1 Jan 2004

Stefansson Hreinn, Steinthorsdottir Valgerdur, Thorgeirsson Thorgeir E, Gulcher Jeffrey R, Stefansson Kari

Abstract excerpt

We discuss in this review the role of the neuregulin (NRG1) gene in schizophrenia. NRG1 contributes to the genetics of schizophrenia in both Icelandic and Scottish schizophrenia patients. NRG1 participates in glutamatergic signaling by regulating the N-methyl-D-aspartate (NMDA) receptor through the interaction of the NRG1 protein and its receptors. NRG1 plays a central role in neural development and is most...

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Source

Identifiers

PMID: 15000348
DOI: 10.1080/07853890310017585

Genes

NRG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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