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Article

Gene expression of neuregulin-1 isoforms in different brain regions of elderly schizophrenia patients.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Mar 2010

Parlapani Eleni, Schmitt Andrea, Wirths Oliver, Bauer Manfred, Sommer Clemens, Rueb Udo, Skowronek Markus H, Treutlein Jens, Petroianu Georg A, Rietschel Marcella, Falkai Peter

Abstract excerpt

One important risk gene in schizophrenia is neuregulin-1 (NRG1), which is expressed in different isoforms in the brain. To determine if alterations of NRG1 are present in schizophrenia, we measured gene expression of NRG1 and its main isoforms as well as the impact of genetic variation of NRG1 in an exploratory study examining three brain regions instead of only one as published so far. In all, we examined...

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Identifiers

PMID: 20218788
DOI: 10.3109/15622970802022376

Genes

NRG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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