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Article

Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury.

The Journal of cell biology - 4 Oct 2010

Xiong Xin, Wang Xin, Ewanek Ronny, Bhat Pavan, Diantonio Aaron, Collins Catherine A

Abstract excerpt

Regenerative responses to axonal injury involve changes in gene expression; however, little is known about how such changes can be induced from a distant site of injury. In this study, we describe a nerve crush assay in Drosophila melanogaster to study injury signaling and regeneration mechanisms. We find that Wallenda (Wnd), a conserved mitogen-activated protein kinase (MAPK) kinase kinase homologous to dual...

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Identifiers

PMID: 20921142
DOI: 10.1083/jcb.201006039
PMCID: PMC2953441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury.PMID 20921142Read ↗

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