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Article

Highwire regulates guidance of sister axons in the Drosophila mushroom body.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 30 Nov 2011

Shin Jung Eun, DiAntonio Aaron

Abstract excerpt

Axons often form synaptic contacts with multiple targets by extending branches along different paths. PHR (Pam/Highwire/RPM-1) family ubiquitin ligases are important regulators of axon development, with roles in axon outgrowth, target selection, and synapse formation. Here we report the function of Highwire, the Drosophila member of the PHR family, in promoting the segregation of sister axons during mushroom body...

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Identifiers

PMID: 22131429
DOI: 10.1523/JNEUROSCI.3902-11.2011
PMCID: PMC3457808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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