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Article

Mek1 kinase governs outcomes of meiotic recombination and the checkpoint response.

Current biology : CB - 12 Oct 2010

Wu Hsin-Yen, Ho Hsuan-Chung, Burgess Sean M

Abstract excerpt

BACKGROUND: Homologous recombination promotes proper segregation of chromosomes during meiosis. Programmed double-strand breaks (DSBs) initiate recombination and are repaired preferentially using the homolog rather than the sister chromatid template. In yeast, activation of Mek1 kinase upholds this bias. Mek1 is also a proposed effector kinase in the recombination checkpoint that responds to aberrant DNA and/or...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20888230
DOI: 10.1016/j.cub.2010.09.016
PMCID: PMC2989795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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