A meiosis-specific protein kinase homolog required for chromosome synapsis and recombination.

Abstract excerpt

The mek1 (meiotic kinase) mutant of Saccharomyces cerevisiae was isolated in a screen for sporulation-proficient, meiotic-lethal mutants. Diploids homozygous for a mek1 null mutation produce only 13% viable spores. mek1 spore inviability is rescued by a spo13 mutation, which causes cells to bypass the meiosis I division. In a mek1 null mutant, meiotic recombination is reduced but not completely eliminated....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Recombination, Genetic
• Share to Amino Acid Sequence
• Share to Base Sequence