Article
Meiotic cells monitor the status of the interhomolog recombination complex.
Genes & development - 1 Jan 1997
Xu L, Weiner B M, Kleckner N
Abstract excerpt
During meiosis, mutations that cause defects at intermediate stages in the recombination process confer arrest at the end of prophase (e.g., pachytene). In yeast, mutations of this type include rad50S, dmc1, rad51, and zip1. Rad50 is likely part of a recombination initiation complex. DMC1, RAD51, and ZIP1 encode two RecA homologs and a synaptonemal complex protein, respectively. We report here the effects of...
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