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Article

Association between APOE genotype, neuropathology and dementia in the older population of England and Wales.

Neuropathology and applied neurobiology - 1 Apr 2011

Nicoll J A R, Savva G M, Stewart J, Matthews F E, Brayne C, Ince P

Abstract excerpt

AIMS: Apolipoprotein E (APOE) genotype is the major genetic risk factor for sporadic Alzheimer's disease (AD) but it is unclear how this is mediated. Most studies of APOE genotype have used case-control design to compare groups differing by two variables: i.e. dementia and AD pathology, so it is unclear to which of these variables APOE genotype is more strongly related. The prospective Medical Research Council...

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Source

Identifiers

PMID: 20880354
DOI: 10.1111/j.1365-2990.2010.01130.x

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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