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Article

APOE genotype, family history of dementia, and Alzheimer disease risk: a 6-year follow-up study.

Archives of neurology - 1 Dec 2004

Huang Wenyong, Qiu Chengxuan, von Strauss Eva, Winblad Bengt, Fratiglioni Laura

Abstract excerpt

BACKGROUND: Both family aggregation and apolipoprotein E (APOE) epsilon4 allele are well-known risk factors for dementia, but the relation between these two factors remains unclear. OBJECTIVE: To explore whether the risk of dementia and Alzheimer disease (AD) due to a positive family history is explained by APOE genotypes. DESIGN: Community-based cohort study. SETTING: The Kungsholmen district of Stockholm,...

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Identifiers

PMID: 15596614
DOI: 10.1001/archneur.61.12.1930

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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