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Article

Sociability and motor functions in Shank1 mutant mice.

Brain research - 22 Mar 2011

Silverman Jill L, Turner Sarah M, Barkan Charlotte L, Tolu Seda S, Saxena Roheeni, Hung Albert Y, Sheng Morgan, Crawley Jacqueline N

Abstract excerpt

Autism is a neurodevelopmental disorder characterized by aberrant reciprocal social interactions, impaired communication, and repetitive behaviors. While the etiology remains unclear, strong evidence exists for a genetic component, and several synaptic genes have been implicated. SHANK genes encode a family of synaptic scaffolding proteins located postsynaptically on excitatory synapses. Mutations in SHANK genes...

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Identifiers

PMID: 20868654
DOI: 10.1016/j.brainres.2010.09.026
PMCID: PMC3041833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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