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Article

Early communication deficits in the Shank1 knockout mouse model for autism spectrum disorder: Developmental aspects and effects of social context.

Autism research : official journal of the International Society for Autism Research - 1 Jun 2016

Sungur A Özge, Schwarting Rainer K W, Wöhr Markus

Abstract excerpt

Alterations in SHANK genes were repeatedly reported in autism spectrum disorder (ASD). ASD is a group of neurodevelopmental disorders diagnosed by persistent deficits in social communication/interaction across multiple contexts, with restricted/repetitive patterns of behavior. To date, diagnostic criteria for ASD are purely behaviorally defined and reliable biomarkers have still not been identified. The validity...

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PMID: 26419918
DOI: 10.1002/aur.1564

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