Article

Comprehensive Analysis of Two <i>Shank3</i> and the Cacna1c Mouse Models of Autism Spectrum Disorder

2016-09-02

Abstract excerpt

To expand, analyze and extend published behavioral phenotypes relevant to autism spectrum disorder (ASD), we present a study of three ASD genetic mouse models: Feng’s Shank3 tm2Gfng model, hereafter Shank3/F , Jiang’s Shank3 tm1Yhj model, hereafter Shank3/J , and the Cacna1c deletion model. The Shank3/F and Shank3/J models mimick gene mutations associated with Phelan-Mcdermid syndrome and the Cacna1c model...

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Literature Corpus work: 40c86542-d364-57fd-a744-09a51034f4e1
DOI: 10.1101/068866

Open publication

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