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The effects of culture on genomic imprinting profiles in human embryonic and fetal mesenchymal stem cells

1 Jan 2011

Abstract excerpt

Human embryonic stem (hES) cells and fetal mesenchymal stem cells (fMSC) offer great potential for regenerative therapy strategies. It is therefore important to characterise the properties of these cells in vitro. One major way the environment impacts on cellular physiology is through changes to epigenetic mechanisms. Genes subject to epigenetic regulation via genomic imprinting have been characterised...

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PMID: 20864803
DOI: 10.4161/epi.6.1.13361

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