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Article

Variable allelic expression of imprinted genes in human pluripotent stem cells during differentiation into specialized cell types in vitro.

Biochemical and biophysical research communications - 4 Apr 2014

Park Sang-Wook, Kim Jihoon, Park Jong-Lyul, Ko Ji-Yun, Im Ilkyun, Do Hyo-Sang, Kim Hyemin, Tran Ngoc-Tung, Lee Sang-Hun, Kim Yong Sung, Cho Yee Sook, Lee Dong Ryul, Han Yong-Mahn

Abstract excerpt

Genomic imprinting is an epigenetic phenomenon by which a subset of genes is asymmetrically expressed in a parent-of-origin manner. However, little is known regarding the epigenetic behaviors of imprinted genes during human development. Here, we show dynamic epigenetic changes in imprinted genes in hESCs during in vitro differentiation into specialized cell types. Out of 9 imprinted genes with single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24613840
DOI: 10.1016/j.bbrc.2014.02.141

Genes

KCNK9
OSBPL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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