Article
Epigenetic analysis and suitability of amniotic fluid stem cells for research and therapeutic purposes.
Stem cells and development - 1 May 2013
Phermthai Tatsanee, Suksompong Singpetch, Tirawanchai Nednapis, Issaragrisil Surapol, Julavijitphong Suphakde, Wichitwiengrat Suparat, Silpsorn Decha, Pokathikorn Puttachart
Abstract excerpt
Amniotic fluid stem cells (AFSs) are interesting mesenchymal stem cells (MSCs) that are characterized by their great potential for cell proliferation and differentiation compared with other types of MSCs identified to date. However, MSCs in prolonged culture have been found to exhibit defects in genetic stability and differentiation capacity. Epigenetic anomalies have been hypothesized to be a cause of these...
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