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Article

PRNP haplotype associated with classical BSE incidence in European Holstein cattle.

PloS one - 16 Sept 2010

Murdoch Brenda M, Clawson Michael L, Yue Samuel, Basu Urmila, McKay Stephanie, Settles Matthew, Capoferri Rossana, Laegreid William W, Williams John L, Moore Stephen S

Abstract excerpt

BACKGROUND: Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease of cattle. The bovine prion gene (PRNP) contains regions of both high and low linkage disequilibrium (LD) that appear to be conserved across Bos taurus populations. The region of high LD, which spans the promoter and part of intron 2, contains polymorphic loci that have been associated with classical BSE status. However, the...

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Identifiers

PMID: 20862290
DOI: 10.1371/journal.pone.0012786
PMCID: PMC2940907

Genes

PRNP

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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