Article
Gene and haplotype polymorphisms of the Prion gene (PRNP) in Japanese Brown, Japanese native and Holstein cattle.
Animal science journal = Nihon chikusan Gakkaiho - 1 Oct 2009
Msalya George, Shimogiri Takeshi, Okamoto Shin, Kawabe Kotaro, Minezawa Mitsuru, Namikawa Takao, Maeda Yoshizane
Abstract excerpt
Polymorphisms in the prion protein gene (PRNP) are known to be associated with transmissible spongiform encephalopathies in human, sheep and goats. There is tentative association between PRNP promoter polymorphism and bovine spongiform encephalopathy (BSE) susceptibility in cattle. In this study, we genotyped for six bovine PRNP polymorphic sites including a 23-bp indel in the promoter, a 12-bp indel in the...
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