Article
PRNP promoter polymorphisms are associated with BSE susceptibility in Swiss and German cattle.
BMC genetics - 16 Apr 2007
Haase Bianca, Doherr Marcus G, Seuberlich Torsten, Drögemüller Cord, Dolf Gaudenz, Nicken Petra, Schiebel Katrin, Ziegler Ute, Groschup Martin H, Zurbriggen Andreas, Leeb Tosso
Abstract excerpt
BACKGROUND: Non-synonymous polymorphisms within the prion protein gene (PRNP) influence the susceptibility and incubation time for transmissible spongiform encephalopathies (TSE) in some species such as sheep and humans. In cattle, none of the known polymorphisms within the PRNP coding region has a major influence on susceptibility to bovine spongiform encephalopathy (BSE). Recently, however, we demonstrated an...
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