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Article

A major genetic component of BSE susceptibility.

BMC biology - 2 Oct 2006

Juling Katrin, Schwarzenbacher Hermann, Williams John L, Fries Ruedi

Abstract excerpt

BACKGROUND: Coding variants of the prion protein gene (PRNP) have been shown to be major determinants for the susceptibility to transmitted prion diseases in humans, mice and sheep. However, to date, the effects of polymorphisms in the coding and regulatory regions of bovine PRNP on bovine spongiform encephalopathy (BSE) susceptibility have been considered marginal or non-existent. Here we analysed two...

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Source

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Identifiers

PMID: 17014722
DOI: 10.1186/1741-7007-4-33
PMCID: PMC1601964

Genes

PRNP

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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