Article
Association of a bovine prion gene haplotype with atypical BSE.
PloS one - 19 Mar 2008
Clawson Michael L, Richt Juergen A, Baron Thierry, Biacabe Anne-Gaëlle, Czub Stefanie, Heaton Michael P, Smith Timothy P L, Laegreid William W
Abstract excerpt
BACKGROUND: Atypical bovine spongiform encephalopathies (BSEs) are recently recognized prion diseases of cattle. Atypical BSEs are rare; approximately 30 cases have been identified worldwide. We tested prion gene (PRNP) haplotypes for an association with atypical BSE. METHODOLOGY/PRINCIPLE FINDINGS: Haplotype tagging polymorphisms that characterize PRNP haplotypes from the promoter region through the three prime...
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