Article
Effect of bovine PRNP gene polymorphisms on BSE susceptibility in cattle.
Folia biologica - 1 Jan 2007
Gurgul Artur, Słota Ewa
Abstract excerpt
Prion protein gene (PRNP) variants determine the susceptibility of humans, sheep and mice to prion diseases, whereas polymorphisms in the open reading frame (ORF) of bovine PRNP seem to be unrelated to the incidence of bovine spongiform encephalopathy (BSE). According to the latest reports, the genetic susceptibility of cattle to BSE is associated with polymorphisms ofthe regulatory region of the PRNP gene and...
Topics
- Animals
- Cattle
- Encephalopathy, Bovine Spongiform
- Genetic Predisposition to Disease
- Polymorphism, Genetic
- Prions
