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Article

Frequencies of polymorphisms associated with BSE resistance differ significantly between Bos taurus, Bos indicus, and composite cattle.

BMC veterinary research - 22 Sept 2008

Brunelle Brian W, Greenlee Justin J, Seabury Christopher M, Brown Charles E, Nicholson Eric M

Abstract excerpt

BACKGROUND: Transmissible spongiform encephalopathies (TSEs) are neurodegenerative diseases that affect several mammalian species. At least three factors related to the host prion protein are known to modulate susceptibility or resistance to a TSE: amino acid sequence, atypical number of octapeptide repeats, and expression level. These factors have been extensively studied in breeds of Bos taurus cattle in...

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Identifiers

PMID: 18808703
DOI: 10.1186/1746-6148-4-36
PMCID: PMC2569919

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PRNP

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