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Article

The identification of candidate genes and SNP markers for classical bovine spongiform encephalopathy susceptibility.

Prion - 1 Jan 2000

Thomson Jennifer M, Bowles Victoria, Choi Jung-Woo, Basu Urmila, Meng Yan, Stothard Paul, Moore Stephen

Abstract excerpt

Classical bovine spongiform encephalopathy is a transmissible prion disease that is fatal to cattle and is a human health risk due to its association with a strain of Creutzfeldt-Jakob disease (vCJD). Mutations to the coding region of the prion gene (PRNP) have been associated with susceptibility to transmissible spongiform encephalopathies in mammals including bovines and humans. Additional loci such as the...

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Source

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Identifiers

PMID: 22918267
DOI: 10.4161/pri.21866
PMCID: PMC3510855

Genes

PRNP
RARB
STMN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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