Article
Hepatitis C virus quasispecies in chronically infected children subjected to interferon-ribavirin therapy.
Archives of virology - 1 Dec 2010
Figlerowicz Magdalena, Jackowiak Paulina, Formanowicz Piotr, Kędziora Paweł, Alejska Magdalena, Malinowska Nelli, Błażewicz Jacek, Figlerowicz Marek
Abstract excerpt
Accumulating evidence suggests that certain features of hepatitis C virus (HCV), especially its high genetic variability, might be responsible for the low efficiency of anti-HCV treatment. Here, we present a bioinformatic analysis of HCV-1a populations isolated from 23 children with chronic hepatitis C (CHC) subjected to interferon-ribavirin therapy. The structures of the viral quasispecies were established based...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
