Article
High diversity of hepatitis C viral quasispecies is associated with early virological response in patients undergoing antiviral therapy.
Hepatology (Baltimore, Md.) - 1 Dec 2009
Fan Xiaofeng, Mao Qing, Zhou Donghui, Lu Yang, Xing Jianwei, Xu Yanjuan, Ray Stuart C, Di Bisceglie Adrian M
Abstract excerpt
UNLABELLED: Differential response patterns to optimal antiviral therapy, peginterferon alpha plus ribavirin, are well documented in patients with chronic hepatitis C virus (HCV) infection. Among many factors that may affect therapeutic efficiency, HCV quasispecies (QS) characteristics have been a major focus of previous studies, yielding conflicting results. To obtain a comprehensive understanding of the role of...
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