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Article

Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases.

Inflammatory bowel diseases - 1 Jan 2011

Frank Daniel N, Robertson Charles E, Hamm Christina M, Kpadeh Zegbeh, Zhang Tianyi, Chen Hongyan, Zhu Wei, Sartor R Balfour, Boedeker Edgar C, Harpaz Noam, Pace Norman R, Li Ellen

Abstract excerpt

BACKGROUND: Abnormal host-microbe interactions are implicated in the pathogenesis of inflammatory bowel diseases. Previous 16S rRNA sequence analysis of intestinal tissues demonstrated that a subset of Crohn's disease (CD) and ulcerative colitis (UC) samples exhibited altered intestinal-associated microbial compositions characterized by depletion of Bacteroidetes and Firmicutes (particularly Clostridium taxa). We...

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Identifiers

PMID: 20839241
DOI: 10.1002/ibd.21339
PMCID: PMC3834564

Genes

NOD2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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