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Article

Complex host genetics influence the microbiome in inflammatory bowel disease

2 Dec 2014

Abstract excerpt

BACKGROUND: Human genetics and host-associated microbial communities have been associated independently with a wide range of chronic diseases. One of the strongest associations in each case is inflammatory bowel disease (IBD), but disease risk cannot be explained fully by either factor individually. Recent findings point to interactions between host genetics and microbial exposures as important contributors to...

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PMID: 25587358
DOI: 10.1186/s13073-014-0107-1

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