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Article

Beta1-adrenergic receptor gene polymorphisms and response to beta1-adrenergic receptor blockade in patients with essential hypertension.

Clinical cardiology - 1 Jun 2004

Karlsson J, Lind L, Hallberg P, Michaëlsson K, Kurland L, Kahan T, Malmqvist K, Ohman K P, Nyström F, Melhus H

Abstract excerpt

BACKGROUND: Studies suggest that the Ser49Gly and Arg389Gly polymorphisms in the beta1-adrenergic receptor might be of functional importance for the cardiovascular system. Both have been associated with altered receptor activity in vitro, and with hypertension and cardiac failure in vivo. HYPOTHESIS: The aim of this study was to test whether these polymorphisms were associated with the change in heart rate or...

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Share to Adrenergic beta-Antagonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Rate

Share to Hypertension

Share to Hypertrophy, Left Ventricular

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Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Adrenergic, beta

Source

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Identifiers

PMID: 15237695
DOI: 10.1002/clc.4960270610
PMCID: PMC6654438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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