Article
Contribution of functional KIR3DL1 to ankylosing spondylitis.
Cellular & molecular immunology - 1 Nov 2010
Zvyagin Ivan V, Mamedov Ilgar Z, Britanova Olga V, Staroverov Dmitriy B, Nasonov Evgeni L, Bochkova Anna G, Chkalina Anna V, Kotlobay Alexei A, Korostin Dmitriy O, Rebrikov Denis V, Lukyanov Sergey, Lebedev Yuri B, Chudakov Dmitriy M
Abstract excerpt
Increasing evidence points to a role for killer immunoglobulin-like receptors (KIRs) in the development of autoimmune diseases. In particular, a positive association of KIR3DS1 (activating receptor) and a negative association of KIR3DL1 (inhibitory receptor) alleles with ankylosing spondylitis (AS) have been reported by several groups. However, none of the studies analyzed these associations in the context of...
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