Article
Polymorphisms of KIRs gene and HLA-C alleles in patients with ankylosing spondylitis: possible association with susceptibility to the disease.
Journal of clinical immunology - 1 Jul 2008
Jiao Yu-Lian, Ma Chun-Yan, Wang Lai-Cheng, Cui Bin, Zhang Jie, You Li, Chen Zi-Jiang, Li Jian-Feng, Zhao Yue-Ran
Abstract excerpt
INTRODUCTION: An emerging body of evidence is accumulating to suggest that killer cell immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) class I ligands contribute to the pathogenesis of diverse kinds of autoimmune diseases. However, the functional effects of their polymorphism remain largely unknown to date. Thus, the present study was undertaken to determine the association of the...
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