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Activating killer immunoglobulin-like receptors genes are associated with increased susceptibility to ankylosing spondylitis.

Clinical and experimental immunology - 1 May 2015

Díaz-Peña R, Vidal-Castiñeira J R, Mulero J, Sánchez A, Queiro R, López-Larrea C

Abstract excerpt

The aim of this study was to analyse the association of specific killer cell immunoglobulin-like receptors (KIR) genes and haplotypes with susceptibility to ankylosing spondylitis (AS) and its different clinical manifestations in a Spanish population. The presence or absence of all KIR genes was studied for their association with AS. A total of 176 patients with AS and 435 healthy control subjects were selected...

Topics

Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Genotyping Techniques
HLA-B27 Antigen
Humans
Male
Receptors, KIR
Receptors, KIR3DS1
Spondylitis, Ankylosing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25491925
DOI: 10.1111/cei.12568
PMCID: PMC4408154

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Activating killer immunoglobulin-like receptors genes are associated with increased susceptibility to ankylosing spondylitis.PMID 25491925Read ↗

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