Article
Inhibitory Killer Cell Immunoglobulin-like Receptor KIR3DL1 in Combination with HLA-B Bw4iso Protect Against Ankylosing Spondylitis
Iranian journal of immunology : IJI - 1 Jun 2010
Mousavi Tahereh, Poormoghim Hadi, Moradi Maziar, Tajik Nader, Shahsavar Farhad, Asadifar Behnam
Abstract excerpt
BACKGROUND: The HLA class I molecules serve as ligands for both T cell receptors and killer cell immunoglobulin-like receptors (KIRs). OBJECTIVE: We investigated the HLA-C and HLA-Bw4 alleles as well as KIRs expression on CD56 positive lymphocytes to evaluate whether these genes and molecules could influence Ankylosing Spondylitis (AS) susceptibility, alone or in combination. METHODS: We typed 40 AS patients and...
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