Article
Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis.
Annals of the rheumatic diseases - 1 Apr 2009
Harvey D, Pointon J J, Sleator C, Meenagh A, Farrar C, Sun J Y, Senitzer D, Middleton D, Brown M A, Wordsworth B P
Abstract excerpt
OBJECTIVES: To assess the possible association of killer immunoglobulin-like receptor (KIR) genes, specifically KIR3DL1, KIR3DS1 and KIR3DL2, with ankylosing spondylitis (AS). METHODS: 14 KIR genes were genotyped in 200 UK patients with AS and 405 healthy controls using multiplex polymerase chain reaction. Sequence-specific oligonucleotide probes were used to subtype 368 cases with AS and 366 controls for 12...
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