Article
Association of the KIR3DS1*013 and KIR3DL1*004 alleles with susceptibility to ankylosing spondylitis.
Arthritis and rheumatism - 1 Apr 2010
Díaz-Peña Roberto, Vidal-Castiñeira Jose Ramón, Alonso-Arias Rebeca, Suarez-Alvarez Beatriz, Vicario Jose Luis, Solana Rafael, Collantes Eduardo, López-Vázquez Antonio, Martínez-Borra Jesús, López-Larrea Carlos
Abstract excerpt
OBJECTIVE: The killer cell immunoglobulin-like receptors (KIRs) form a group of regulatory molecules that specifically recognize HLA class I molecules. The aim of this study was to analyze the possible contribution of the KIR3DL1 and KIR3DS1 alleles, in addition to HLA-B27, in the susceptibility to ankylosing spondylitis (AS) in a population of individuals from Spain. METHODS: We genotyped the KIR3DS1 and KIR3DL1...
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