Article
Activating KIR genes are associated with ankylosing spondylitis in Asian populations.
Human immunology - 1 Jul 2008
Díaz-Peña Roberto, Blanco-Gelaz Miguel Angel, Suárez-Alvarez Beatriz, Martínez-Borra Jesús, López-Vázquez Antonio, Alonso-Arias Rebeca, Brüges-Armas Jacome, Vidal-Castiñeira Jose Ramón, López-Larrea Carlos
Abstract excerpt
Killer cell immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) loci are both highly polymorphic. The aim of this study was to perform a KIR genotype analysis and examine, in concert with HLA-B27 genotypes, their influence on ankylosing spondylitis (AS) susceptibility in two Asian populations (one from China, 42 patients and 30 controls, and another from Thailand, 30 patients and 16 controls)....
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