Article
Comparative analysis of methods for detecting interacting loci.
BMC genomics - 5 Jul 2011
Chen Li, Yu Guoqiang, Langefeld Carl D, Miller David J, Guy Richard T, Raghuram Jayaram, Yuan Xiguo, Herrington David M, Wang Yue
Abstract excerpt
BACKGROUND: Interactions among genetic loci are believed to play an important role in disease risk. While many methods have been proposed for detecting such interactions, their relative performance remains largely unclear, mainly because different data sources, detection performance criteria, and experimental protocols were used in the papers introducing these methods and in subsequent studies. Moreover, there...
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