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Article

A "molecular evolution" approach for isolation of intrinsically active (MEK-independent) MAP kinases.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Levin-Salomon Vered, Livnah Oded, Engelberg David

Abstract excerpt

Mitogen-activated protein (MAP) kinases are a large family of enzymes composed of about four subfamilies, each containing several isoforms and splicing variants. Many MAP kinases are coexpressed in each eukaryotic cell and coactivated in response to various stimuli. It is, therefore, difficult to explore the specific downstream effects of each species of MAPK. Expression of an intrinsically active variant of a...

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PMID: 20811988
DOI: 10.1007/978-1-60761-795-2_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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