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Article

Isolation of intrinsically active mutants of MAP kinases via genetic screens in yeast.

Methods (San Diego, Calif.) - 1 Nov 2006

Engelberg David, Livnah Oded

Abstract excerpt

Intrinsically active variants of a protein are powerful tools for deciphering the specific functions of that protein. Since the catalytic activity of such variants is spontaneously active in vivo, they can disclose very accurately biochemical and biological functions of the parental protein. It is particularly important to obtain intrinsically active variants of individual MAP kinases. This is because in response...

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Identifiers

PMID: 16938468
DOI: 10.1016/j.ymeth.2006.06.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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