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Article

Functional analysis of protein kinase networks in living cells: beyond "knock-outs" and "knock-downs".

Methods (San Diego, Calif.) - 1 Nov 2006

Madhani Hiten D

Abstract excerpt

The identification of over 500 protein kinases encoded by the human genome sequence offers one measure of the importance of protein kinase networks in cell biology. High throughput technologies for inactivating genes are producing an awe-inspiring amount of data on the cellular and organismal effects of reducing the levels of individual protein kinases. Despite these technical advances, our understanding of...

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Identifiers

PMID: 16884918
DOI: 10.1016/j.ymeth.2006.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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