Article
Intrinsically active variants of all human p38 isoforms.
The FEBS journal - 1 Feb 2007
Avitzour Michal, Diskin Ron, Raboy Bilha, Askari Nadav, Engelberg David, Livnah Oded
Abstract excerpt
The p38 mitogen-activated protein kinases are activated in response to various extracellular signals in eukaryotic cells and play a critical role in the cellular responses to these signals. The four mammalian isoforms (p38alpha, p38beta, p38gamma, and p38delta) are coexpressed and coactivated in the same cells. The exact role of each p38 isoform has not been entirely identified, in part due to the inability to...
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