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Article

When expressed in yeast, mammalian mitogen-activated protein kinases lose proper regulation and become spontaneously phosphorylated.

The Biochemical journal - 1 Jan 2009

Levin-Salomon Vered, Maayan Inbal, Avrahami-Moyal Liat, Marbach Irit, Livnah Oded, Engelberg David

Abstract excerpt

MAPKs (mitogen-activated protein kinases) are key components in cell signalling pathways. Under optimal growth conditions, their activity is kept off, but in response to stimulation it is dramatically evoked. Because of the high degree of evolutionary conservation at the levels of sequence and mode of activation, MAPKs are believed to share similar regulatory mechanisms in all eukaryotes and to be functionally...

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PMID: 18778243
DOI: 10.1042/BJ20081335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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