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Thr202Ala in thyA is a marker for the Latin American Mediterranean lineage of the Mycobacterium tuberculosis complex rather than para-aminosalicylic acid resistance.

Antimicrobial agents and chemotherapy - 1 Nov 2010

Feuerriegel Silke, Köser Claudio, Trübe Leona, Archer John, Rüsch Gerdes Sabine, Richter Elvira, Niemann Stefan

Abstract excerpt

Single nucleotide polymorphisms (SNPs) involved in the development of resistance represent powerful markers for the rapid detection of first- and second-line resistance in clinical Mycobacterium tuberculosis complex (MTBC) isolates. However, the association between particular mutations and phenotypic resistance is not always clear-cut, and phylogenetic SNPs have been misclassified as resistance markers in the...

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PMID: 20805400
DOI: 10.1128/AAC.00738-10
PMCID: PMC2976163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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