Article
Genotypic and phenotypic characteristics of tunisian isoniazid-resistant Mycobacterium tuberculosis strains.
Journal of microbiology (Seoul, Korea) - 1 Jun 2011
Soudani Alya, Hadjfredj Sondess, Zribi Meriem, Messaadi Feriel, Messaoud Taieb, Masmoudi Afef, Zribi Mohamed, Fendri Chedlia
Abstract excerpt
Forty three isoniazid (INH)-resistant Mycobacterium tuberculosis isolates were characterized on the basis of the most common INH associated mutations, katG315 and mabA -15C→T, and phenotypic properties (i.e. MIC of INH, resistance associated pattern, and catalase activity). Typing for resistance mutations was performed by Multiplex Allele-Specific PCR and sequencing reaction. Mutations at either codon were...
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