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Article

Genetic markers associated with plasma protein C level in African Americans: the atherosclerosis risk in communities (ARIC) study.

Genetic epidemiology - 1 Dec 2014

Munir M Shahzeb, Weng Lu-Chen, Tang Weihong, Basu Saonli, Pankow James S, Matijevic Nena, Cushman Mary, Boerwinkle Eric, Folsom Aaron R

Abstract excerpt

Protein C is an endogenous anticoagulant protein with anti-inflammatory properties. Single-nucleotide polymorphisms (SNPs) affect the levels of circulating protein C in European Americans. We performed a genome-wide association (GWA) scan of plasma protein C concentration with approximately 2.5 million SNPs in 2,701 African Americans in the Atherosclerosis Risk in Communities Study. Seventy-nine SNPs from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25376901
DOI: 10.1002/gepi.21868
PMCID: PMC4354842

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