Article
Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study.
Human molecular genetics - 1 Sept 2017
de Vries Paul S, Yu Bing, Feofanova Elena V, Metcalf Ginger A, Brown Michael R, Zeighami Atefeh L, Liu Xiaoming, Muzny Donna M, Gibbs Richard A, Boerwinkle Eric, Morrison Alanna C
Abstract excerpt
Oligopeptides are important markers of protein metabolism, as they are cleaved from larger polypeptides and proteins. Genetic association studies may help elucidate their origin and function. In 1,552 European Americans and 1,872 African Americans of the Atherosclerosis Risk in Communities study, we performed whole-genome and whole-exome sequencing and measured serum levels of 25 peptides. Common variants (minor...
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