Article
Molecular characteristics in Chinese with chronic lymphocytic leukemia by next-generation sequencing: A single-center retrospective analysis.
International journal of laboratory hematology - 1 Dec 2023
Cao Yanglin, Chen Yan, Tao Tingting, Gong Yanlei, Xu Chao, Cen Jiannong, Shen Hongjie, Pan Jinlan, Chen Suning, Yao Li
Abstract excerpt
INTRODUCTION: Although the prevalence of Asian chronic lymphocytic leukemia (CLL) patients is not as high as that of Caucasians, there are more atypical CLLs in Asia whose genetic characteristics and their clinical significance are distinct and remain unclear. METHODS: A retrospective analysis of 85 CLL samples in our center was conducted from 2019 to 2022. We used next-generation sequencing with a 172 gene panel...
Topics
- Male
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell
- Retrospective Studies
- Myeloid Differentiation Factor 88
- East Asian People
- Mutation
- Prognosis
- High-Throughput Nucleotide Sequencing