Article
Genetic variation and risk of chronic lymphocytic leukaemia.
Seminars in cancer biology - 1 Dec 2010
Crowther-Swanepoel Dalemari, Houlston Richard S
Abstract excerpt
Chronic lymphocytic leukaemia (CLL) is the most common form of lymphoid malignancy in Western countries, accounting for around a quarter of all leukaemias. Evidence from epidemiological and family studies have provided evidence for familial clustering of CLL compatible with inherited genetic predisposition to CLL. Direct evidence for genetic susceptibility has been provided by a recent genome wide association...
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